Nitrile is made from an allergy safe compound that feels a lot like latex but is much stronger and is more comfortable to wear. It is a great combination of strength, comfort, durability and dexterity. Powder free gloves go through an extra process of chlorinating the gloves to ease donning. The 5 mil are considered a medium to heavier grade option that is most popular with mechanics, machinists, sanitation workers, plumbers, HVAC technicians and are food service safe. They come in sizes S, M, L, XL and 2XL. Each case is 10 boxes of 100 (1000 per case).