Nitrile is made from an allergy safe compound that feels a lot like latex but is much stronger, costs less, and is more comfortable to wear. It is a great combination of strength, comfort, durability and dexterity. Powder free gloves go through an extra process of chlorinating to ease donning. The 4 mil are considered a medium grade option that is most popular with custodians, cleanroom workers, mechanics, machinists, food-service workers, plumbers and HVAC technicians. They come in sizes S, M, L, XL and 2XL. Each case is 10 boxes of 100 (1000 per case).